Anti Conglutinin (recombinant, bovine)
Mouse monoclonal antibody
Cat.No. HYB 263-02
Preparation: Protein-A/G purified
Content: Available in 200 µL and 1 mL, 1 mg/mL
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
Storage: In the dark at 4-8ºC
Conglutinin is a plasma protein belonging to the C-type family of collectins. Conglutinin is closely related to surfactant protein A and D and mannan-binding lectin, but has so far conglutinin only been found in Bovidae. Some and maybe all of the C-type collectins bind microbial carbohydrates and subsequently activate the complement system. The molecular mass of conglutinin is app. 40 kDa (1).
Recombinant neck-CRD domain of conglutinin
HYB 263-02 is specific for the C-terminal part of the conglutinin molecule. No cross-reaction to CL-43 is seen in Western blotting.
HYB 263-02 binds to the CRD (carbohydrate recognition domain) region or the a-helical neck region of conglutinin.
Not determined
| Method | Usability | Dilution guideline | References |
| ELISA | Yes | ||
| Immunoblotting | No | ||
| Immunohistochemistry | Not determined |
1. Holmskov UL (2000) Collectins and collectin receptors in innate immunity. APMIS Suppl 100:1-59.
2. Hansen S, Moeller V, Holm D, Vitved L, Bendixen C, Skjodt K, Holmskov U (2002) Novel characterisation of the gene encoding conglutinin reveals that previously characterised promoter corresponds to the CL-43 promoter. Mol Immunol 39:39-43.
